GENERAL HISTOLOGY

Detailed explanation-1: -Blood levels of the pineal hormone melatonin are high at night and low during the day. Its secretion is regulated by a rhythm-generating system located in the suprachiasmatic nucleus of the hypothalamus, which is in turn regulated by light.

Detailed explanation-2: -Melatonin plays an important role in regulating human sleep. Administration of sustained-release or transdermal formulation melatonin reduces sleep latency, increases total sleep time, and improves sleep maintenance [12, 13].

Detailed explanation-3: -Natural melatonin is an important hormone for regulating your sleep-wake cycle. While several factors can negatively affect how long and how well you sleep, the amount of melatonin your pineal gland is making could be one of them. If you’re having issues with sleeping, be sure to talk to your healthcare provider.

Detailed explanation-4: -Melatonin is a hormone that your brain produces in response to darkness. It helps with the timing of your circadian rhythms (24-hour internal clock) and with sleep.