GENERAL HISTOLOGY

Detailed explanation-1: -Aldosterone signals certain organs, like your kidneys and colon, to increase the amount of sodium they send into your bloodstream or the amount of potassium released in your urine (pee). Aldosterone’s effect on sodium increase causes your body to retain water in your blood, which increases blood volume.

Detailed explanation-2: -Aldosterone causes sodium to be absorbed and potassium to be excreted into the lumen by principal cells. In alpha intercalated cells, located in the late distal tubule and collecting duct, hydrogen ions and potassium ions are exchanged. Hydrogen is excreted into the lumen, and the potassium is absorbed.

Detailed explanation-3: -A steroid hormone made by the adrenal cortex (the outer layer of the adrenal gland). It helps control the balance of water and salts in the kidney by keeping sodium in and releasing potassium from the body. Too much aldosterone can cause high blood pressure and a build-up of fluid in body tissues.

Detailed explanation-4: -Volume is regulated through a direct effect on the collecting duct, where aldosterone promotes sodium retention and potassium excretion.

Detailed explanation-5: -aldosterone: A mineralocorticoid hormone that is secreted by the adrenal cortex and regulates the balance of sodium and potassium in the body.