GENERAL HISTOLOGY

Detailed explanation-1: -Chromaffin cells of the adrenal medulla are innervated by the splanchnic nerve and secrete adrenaline (epinephrine), noradrenaline (norepinephrine), some dopamine, enkephalin and enkephalin-containing peptides, and a few other hormones into the blood stream.

Detailed explanation-2: -A type of cell that makes neurohormones (chemicals that are made by nerve cells and used to send signals to other cells) and releases them into the blood. Chromaffin cells make epinephrine (adrenaline) and norepinephrine (noradrenaline).

Detailed explanation-3: -Chromaffin cells are neuroendocrine cells derived from the neural crest 1, 2. They populate the adrenal medulla and extra-adrenal sympathetic paraganglia. The largest accumulation of extra-adrenal chromaffin cells is the organ of Zuckerkandl (OZ) 3–6.

Detailed explanation-4: -Whereas the peripheral nitric-oxide system occurs in the adrenal cortex, chromaffin cells express the nitric-oxide system of the brain.

Detailed explanation-5: -The inner part of the adrenal gland (a small organ on top of each kidney). The adrenal medulla makes chemicals such as epinephrine (adrenaline) and norepinephrine (noradrenaline) which are involved in sending nerve signals.