GENERAL HISTOLOGY

Detailed explanation-1: -Facial plethora is characterized by facial swelling and puffiness. It can cause redness in lighter complexions and brown discoloration in darker skin tones. It’s a main symptom of Cushing syndrome, but it may also be a symptom of SVCS and carcinoid syndrome. Other causes include polycythemia vera, rosacea, and sunburn.

Detailed explanation-2: -People with Cushing’s syndrome may see their face get round ("moon face"), they gain weight in unusual ways, bruise easily or feel weak, tired and sad. Women and men may also notice fertility and other problems. CS is most often found in adults between the ages of 20 and 50.

Detailed explanation-3: -Facial plethora is a clinical sign described since ancient times for a variety of diseases. In the 19th century, it was linked to increased blood volume or flow, but this has never been proven. Facial plethora is also one of the earliest described clinical features of Cushing’s syndrome (CS).