ENDOCRINE SYSTEM
ADRENAL
|
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
|
|
|
24 hour urine free cortisol
|
|
|
Overnight 1 mg DST
|
|
|
Late night salivary cortisol
|
|
|
TSH and FT4
|
Detailed explanation-1: -Doctors may use urine, saliva, or blood tests to diagnose Cushing’s syndrome. Sometimes doctors run a follow-up test to find out if excess cortisol is caused by Cushing’s syndrome or has a different cause.
Detailed explanation-2: -Three first-line diagnostic tests are currently used to screen for CS: measurement of free cortisol in 24-hour urine (UFC), cortisol suppressibility by low doses of dexamethasone (DST), and assessment of cortisol circadian rhythm using late-night serum and/or salivary cortisol.
Detailed explanation-3: -As mentioned above, TSH levels increase after successful surgery for Cushing’s syndrome. The increase of thyroid hormones levels and the inability to adequate suppress TSH detected in SITS patients can be due to an impaired deiodinase activity.