ENDOCRINE SYSTEM
ENDOCRINE
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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True
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False
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Either A or B
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None of the above
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Detailed explanation-1: -Steroid hormones are insoluble in water; they are carried by transport proteins in blood. As a result, they remain in circulation longer than peptide hormones.
Detailed explanation-2: -Like cholesterol, steroid hormones are not soluble in water (they are hydrophobic). Because blood is water-based, lipid-derived hormones must travel to their target cell bound to a transport protein.
Detailed explanation-3: -All three steroids have low water solubility, which increases considerably at sonication for testosterone and estradiol-17 beta. The phosphatidylcholine vesicles have a very small solubilising capacity for the steroids; about 20 mumol/mol.
Detailed explanation-4: -Steroid hormones can be classified as lipid soluble hormones. This means that steroid hormones can diffuse lipid based substances, but not water based substances. Considering blood is a water based substance, steroid hormones must be transported through the blood to target cells via protein carriers.