GENERAL HISTOLOGY

Detailed explanation-1: -Prolactin is synthesized by lactotrophs in the anterior pituitary gland. The number of lactotrophs will increase during pregnancy in response to the physiological need to develop breast tissues and to prepare for milk production.

Detailed explanation-2: -The pituitary is a small gland in the middle of the head just below the brain (figure 1). The pituitary contains lactotroph cells that produce prolactin, the hormone that stimulates lactation (production of breast milk).

Detailed explanation-3: -Prolactin is produced mainly by the lactotroph cells in the anterior pituitary. PRL is under the inhibitory control by dopamine released from the tuberoinfundibular dopaminergic (TIDA) neurons (1).

Detailed explanation-4: -Anatomy of the Pituitary Gland It regulates growth, metabolism, and reproduction through the hormones that it produces. The production of these hormones is either stimulated or inhibited by chemical messages sent from the hypothalamus to the pituitary. The posterior lobe produces two hormones, vasopressin and oxytocin.

Detailed explanation-5: -Production of prolactin is controlled by two main hormones: dopamine and estrogen. These hormones send a message to the pituitary gland primarily indicating whether to begin or cease the production of prolactin. Dopamine restrains the production of prolactin, while estrogen increases it.