GENERAL HISTOLOGY

Detailed explanation-1: -Glucagon increases blood glucose levels, whereas insulin decreases them. Somatostatin inhibits both, glucagon and insulin release, 6 whereas PP regulates the exocrine and endocrine secretion activity of the pancreas.

Detailed explanation-2: -Glucagon is a glucoregulatory peptide hormone that counteracts the actions of insulin by stimulating hepatic glucose production and thereby increases blood glucose levels.

Detailed explanation-3: -When blood glucose levels fall too low (low blood glucose), the pancreas pumps out more glucagon. This hormone helps blood glucose rise back up in multiple ways: It causes the liver to convert stored glucose into a usable form and then release it into the bloodstream.

Detailed explanation-4: -After eating, when there is too much glucose to be used, the extra glucose is converted to glycogen to be stored. When blood glucose levels drop the glycogen gets converted back to glucose and is released into the bloodstream to be used. Glucagon signals the body to convert the stored glycogen back into glucose.

Detailed explanation-5: -Glucagon is secreted by the alpha cells of the pancreatic islets in much the same manner as insulin-except in the opposite direction. If blood glucose is high, then no glucagon is secreted. When blood glucose goes low, however (such as between meals, and during exercise), more and more glucagon is secreted.