GENERAL HISTOLOGY

Detailed explanation-1: -A high calcium-phosphate product is thought to increase the risk of soft tissue calcification in hypoparathyroidism, including cataracts. Based on small case series, cataracts in hypoparathyroidism typically develop in the posterior subcapsular region of the lens.

Detailed explanation-2: -Furthermore, secondary hyperparathyroidism, the most significant complication in patients with chronic kidney disease, causes abnormal bone disorders as well as extraskeletal calcification, such as vascular and valvular calcification, and increased risk of cardiovascular mortality.

Detailed explanation-3: -Such symptoms include clouding of the lens of the eyes (cataracts), seizures or convulsions, fainting, abnormal heartbeats (cardiac arrhythmias) and, potentially, signs of congestive heart failure. Some individuals may develop calcium deposits (calcifications) in the brain or the kidneys.