GENERAL HISTOLOGY

Detailed explanation-1: -Surgery is the most common treatment for primary hyperparathyroidism and provides a cure in most cases. A surgeon will remove only those glands that are enlarged or have a tumor.

Detailed explanation-2: -People with primary hyperparathyroidism (PHPT) may have reduced bone mineral density, which increases the risk of fragility fractures. Bisphosphonates are a class of drug that reduces bone loss and increase bone mineral density.

Detailed explanation-3: -Cinacalcet is the drug of choice for managing hypercalcemia, whereas bisphosphonates or denosumab improves BMD. Combined therapy with cinacalcet and a bisphosphonate or cinacalcet and denosumab should be considered if the effects on serum calcium and BMD are simultaneously desired.