GENERAL HISTOLOGY

ENDOCRINE SYSTEM

THYROID FOLLICULAR CELL

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
a 25 year old woman presented with goiter, myxedma and exopthalmus. she would have autoantibodies against?
A
tsh receptor
B
thyroglobin
C
thyroid peroxidase
D
na/i symporter
E
pendrin
Explanation: 

Detailed explanation-1: -Graves’ disease includes thyrotoxicosis, goiter, exophthalmos, and pretibial myxedema when fully expressed, but can occur with one or more of these features. Graves’ disease is a disease of “autoimmunity", but the final cause of autoimmunity remains unclear. A strong hereditary tendency is present.

Detailed explanation-2: -The presence of TPO antibodies in your blood suggests that the cause of thyroid disease is an autoimmune disorder, such as Hashimoto’s disease or Graves’ disease. In autoimmune disorders, your immune system makes antibodies that mistakenly attack normal tissue.

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