GENERAL HISTOLOGY

Detailed explanation-1: -Iodine deficiency is the most common cause of goiter. The body needs iodine to produce thyroid hormone. If you do not have enough iodine in your diet, the thyroid gets larger to try and capture all the iodine it can, so it can make the right amount of thyroid hormone.

Detailed explanation-2: -Iodine deficiency is the most common cause of thyroid disease and, if serious, can cause permanent brain damage and intellectual disability in babies. Iodine is a mineral found naturally in seawater and soil. The body needs iodine to make thyroid hormone in the thyroid gland.

Detailed explanation-3: -The most common cause of goiters worldwide is a lack of iodine in the diet. In the United States, where the use of iodized salt is common, goiters are caused by conditions that change thyroid function or factors that affect thyroid growth.

Detailed explanation-4: -It’s true that not having enough iodine (iodine deficiency) can cause hypothyroidism. But iodine deficiency has been rare in the United States and other developed countries since iodine has been added to salt (iodized salt) and other foods.

Detailed explanation-5: -In iodine sufficient individuals, iodine excess causes elevated thyroid-stimulating hormone levels, which inhibits thyroid hormone production leading to hypothyroidism and goiter.