GENERAL HISTOLOGY

Detailed explanation-1: -Hashimoto’s disease is an autoimmune disorder affecting the thyroid gland. The thyroid is a butterfly-shaped gland located at the base of the neck just below the Adam’s apple. The thyroid produces hormones that help regulate many functions in the body.

Detailed explanation-2: -WHAT CAUSES THYROIDITIS? Thyroiditis is caused by an attack on the thyroid, causing inflammation and damage to the thyroid cells. Antibodies that attack the thyroid cause most types of thyroiditis. As such, thyroiditis is often an autoimmune disease, like juvenile (type 1) diabetes and rheumatoid arthritis.

Detailed explanation-3: -Acute phase-Lasts 3-6 weeks and presents primarily with pain; symptoms of hyperthyroidism also may be present. Transient asymptomatic and euthyroid phase-Lasts 1-3 weeks. Hypothyroid phase-Lasts from weeks to months; it may become permanent in 5-15% of patients.

Detailed explanation-4: -Thyroiditis is a group of inflammatory thyroid disorders. Patients with chronic lymphocytic thyroiditis (also referred to as Hashimoto’s thyroiditis) present with hypothyroidism, goiter, or both. Measurement of serum thyroid autoantibodies and thyroglobulin confirms the diagnosis.