GENERAL HISTOLOGY

EPITHELIUM

CELL JUNCTION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Urine is confined to the human bladder in part due to the structure of junctions that connect the cells lining the bladder. These junctions form a barrier that prevents the exchange of ions and solutes between the blood and urine. What is the likely identity of these junctions?
A
Gap junctions
B
Tight junctions
C
Desmosomes
D
Plasmodesmata
Explanation: 

Detailed explanation-1: -What is the likely identity of these junctions? Explanation: Tight junctions commonly line organs such as the urinary bladder, as they prevent unwanted fluid from leaking into or out of these organs. They are most notable for their barrier function: they are almost completely impermeable to fluid.

Detailed explanation-2: -Urine is confined to the human bladder in part due to the structure of junctions that connect the cells lining the bladder. These junctions form a barrier that prevents the exchange of ions and solutes between the blood and urine.

Detailed explanation-3: -The purpose of tight junctions is to keep liquid from escaping between cells, allowing a layer of cells (for instance, those lining an organ) to act as an impermeable barrier. For example, the tight junctions between the epithelial cells lining your bladder prevent urine from leaking out into the extracellular space.

Detailed explanation-4: -Desmosome junctions are known as macula adherens and are found mostly in tissue needing strong support, such as cardiac, gastrointestinal, and bladder tissue.

Detailed explanation-5: -Tight junctions form watertight connections between adjacent animal cells. Proteins create tight junction adherence. This tight adherence prevents materials from leaking between the cells; tight junctions are typically found in epithelial tissues that line internal organs and cavities, and comprise most of the skin.

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