GENERAL HISTOLOGY

EPITHELIUM

CELL JUNCTION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Which type of cellular junction form a “quilted seal” between cells?
A
Tight junctions
B
Desmosomes
C
Gap Junctions
D
None of the above
Explanation: 

Detailed explanation-1: -Plasmodesmata are intercellular junctions between plant cells that enable the transportation of materials between cells. A tight junction is a watertight seal between two adjacent animal cells, which prevents materials from leaking out of cells.

Detailed explanation-2: -Occluding junctions The borders of two cells are fused together, often around the whole perimeter of each cell, forming a continuous belt like junction known as a tight junction or zonula occludens (zonula = latin for belt).

Detailed explanation-3: -1. Occluding junctions seal cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other. 2. Anchoring junctions mechanically attach cells (and their cytoskeletons) to their neighbors or to the extracellular matrix.

Detailed explanation-4: -Tight junctions, also known as Zonula Occludens, are cell-cell adhesion complexes that play a role in the organization of epithelial tissue.

Detailed explanation-5: -Tight junctions include occludin, claudin family members, JAMs 1–3, cingulin, and linker proteins from the ZO family, which serve to bind the former proteins to each other or to the actin cytoskeleton. In both endothelial and epithelial cells, VASP has been found in the complex with zonula occludens-1 (ZO-1) protein.

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