GENERAL HISTOLOGY

Detailed explanation-1: -Animal cell cleavage furrow formation is caused by a ring of actin microfilaments called the contractile ring, which forms during early anaphase. Cleavage is driven by these motor proteins, actin and myosin, which are the same proteins involved with muscle contraction.

Detailed explanation-2: -To complete the cell cycle, the cleavage furrow draws the plasma membrane toward the cell center, pinching the cytoplasm into two lobes that are subsequently separated into two cells. The position of the cleavage furrow is induced by the mitotic spindle during early anaphase.

Detailed explanation-3: -This furrow is created by the same proteins that allow muscle cells to contract: actin and myosin. These proteins, which have the ability to expand or contract, form a “contractile ring” that begins squeezing the cell along its middle.