GENERAL HISTOLOGY

Detailed explanation-1: -The basal lamina, a mixture of glycoproteins and collagen, provides an attachment site for the epithelium, separating it from underlying connective tissue. The basal lamina attaches to a reticular lamina, which is secreted by the underlying connective tissue, forming a basement membrane that helps hold it all together.

Detailed explanation-2: -Epithelial cells attach to their basement membrane via integrins. Integrins in the plasma membrane associate with components of the basement membrane, mostly laminin and fibronectin. Basement membrane restricts migration of metastatic cells.

Detailed explanation-3: -The basement membrane (BM) is a special type of extracellular matrix that lines the basal side of epithelial and endothelial tissues.

Detailed explanation-4: -The basement membrane, also known as basal lamina, is a thin, dense layer of extracellular matrix that lines most human tissues forming the supporting structure and scaffolding for epithelial tissue and separates different types of cells, such as nerve cells and muscle cells.

Detailed explanation-5: -The basal lamina helps to attach and anchor the cells to the underlying connective tissue. Proteins (integrins and proteglycans) in the cell membranes attach to proteins in the basal lamina, which in turn is linked to the extracellular matrix of connective tissue.