GENERAL HISTOLOGY

Detailed explanation-1: -Sebaceous glands are holocrine glands found over the entire surface of the body except the palms, soles and dorsum of the feet. They are largest and most concentrated in the face and scalp where they are the sites of origin of acne (Fig.

Detailed explanation-2: -Sebaceous glands produce sebum via holocrine secretion, a largely uncharacterized mode of programmed cell death that contributes to the homeostasis and barrier function of the skin.

Detailed explanation-3: -Sebaceous glands are holocrine glands, and sweat glands (both eccrine and apocrine ones) are merocrine glands.

Detailed explanation-4: -Examples of holocrine glands include the sebaceous glands of the skin and the meibomian glands of the eyelid. The sebaceous gland is an example of a holocrine gland because its product of secretion (sebum) is released with remnants of dead cells.

Detailed explanation-5: -Holocrine secretion is a specific mode of secretion involving secretion of entire cytoplasmic materials with remnants of dead cells, as observed in multicellular exocrine glands of reptiles, birds, and mammals.