GENERAL HISTOLOGY

Detailed explanation-1: -As the blood plasma flows through the nephrons, its composition changes. Fluids comprising excess water, salt and metabolic waste products are extracted from the blood as it enters the Bowman’s capsule in the nephrons. This fluid in the Bowman’s capsule is called glomerular filtrate.

Detailed explanation-2: -The process by which glomerular filtration occurs is called renal ultrafiltration. The force of hydrostatic pressure in the glomerulus (the force of pressure exerted from the pressure of the blood vessel itself) is the driving force that pushes filtrate out of the capillaries and into the slits in the nephron.

Detailed explanation-3: -These filters aid in clearing the blood of waste and extra fluid. Glomerular filtration seems to occur in the glomerulus where blood is filtered. The process occurs across the 3 layers-the epithelium of Bowman’s capsule, the endothelium of glomerular blood vessels, & a membrane between these two layers.

Detailed explanation-4: -Blood enters the glomerulus through the afferent arteriole at the vascular pole, undergoes filtration in the glomerular capillaries, and exits the glomerulus through the efferent arteriole at the vascular pole.

Detailed explanation-5: -The glomerulus filters water and small solutes out of the bloodstream. The resulting filtrate contains waste, but also other substances the body needs: essential ions, glucose, amino acids, and smaller proteins. When the filtrate exits the glomerulus, it flows into a duct in the nephron called the renal tubule.