GENERAL HISTOLOGY

Detailed explanation-1: -Filtration is a non-selective process performed by the glomerulus using the glomerular capillary blood pressure. About 1200 ml of blood is filtered by the glomerulus per minute to form 125 ml of filtrate in the Bowman’s capsule per composition as that of plasma except the nitrogenous wastes.

Detailed explanation-2: -Renal Glomerular Filtration: Glomerular filtration is a passive, nonselective process in which hydrostatic pressure (approximately 10 mm Hg) forces fluids and small (<5 nm) hydrophilic particles through the glomerular membrane (Deen et al., 2001).

Detailed explanation-3: -The process by which glomerular filtration occurs is called renal ultrafiltration. The force of hydrostatic pressure in the glomerulus (the force of pressure exerted from the pressure of the blood vessel itself) is the driving force that pushes filtrate out of the capillaries and into the slits in the nephron.

Detailed explanation-4: -Thus glomerular filtration is non selective as, though all substances must move through the glomerular membrane i.e. plasma and dissolved substances but no blood cells and large blood proteins.

Detailed explanation-5: -Filtration is least selective because hydrostatic pressure forces the entry of water and solutes to the glomerulus. All the body fluids undergo a filtration mechanism. Negative charges and effective size of the pores present on the glomerulus membrane make the filtration least selective.