GENERAL HISTOLOGY

Detailed explanation-1: -When you eat proteins, the body breaks them down into amino acids. Ammonia is produced from leftover amino acids, and it must be removed from the body. The liver produces several chemicals (enzymes) that change ammonia into a form called urea, which the body can remove in the urine.

Detailed explanation-2: -Ammonia can be produced by the break-down of amino acids, or by the gut bacteria in humans. If the level of ammonia in the blood becomes too high, then it becomes toxic to the brain. The urea cycle removes ammonia from the blood and makes urea, which is eventually excreted as urine.

Detailed explanation-3: -Urea, commonly referred to as blood urea nitrogen (BUN) when measured in the blood, is a product of protein metabolism. BUN is considered a non-protein nitrogenous (NPN) waste product. Amino acids derived from the breakdown of protein are deaminated to produce ammonia.

Detailed explanation-4: -The answer is that, other than ammonia, urea has the highest nitrogen content of all industrial chemicals and is in high demand as a fertilizer. In the soil, it decomposes back to ammonia (actually ammonium ion) and carbon dioxide.

Detailed explanation-5: -Urea is naturally produced when the liver breaks down protein or amino acids, and ammonia. The kidneys then transfer the urea from the blood to the urine. Extra nitrogen is expelled from the body through urea, and because it is extremely soluble, it is a very efficient process.