GENERAL HISTOLOGY

EXCRETORY SYSTEM

KIDNEY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Describe bone formation in CKD
A
Bone turnover is low causing bones to become weak and brittle
B
Bone turnover is high causing bones to become strong and resilient
C
Bone turnover is high causing bones to become weak and brittle
D
Bone formation is unaffected in CKD
Explanation: 

Detailed explanation-1: -Damaged kidneys can’t change vitamin D to the active usable form and this can lead to bone weakness. In kidney disease too much parathyroid hormone is released to keep calcium levels in the blood balanced. By taking calcium from the bones the bones become weaker.

Detailed explanation-2: -Damaged kidneys must work harder to remove phosphorus from your body. Buildup of phosphorus is associated with less calcium in your blood and with the release of PTH by your parathyroid glands. PTH moves calcium out of your bones and into your blood. The loss of calcium can harm your bones.

Detailed explanation-3: -To keep your bones strong, your kidneys must keep the right balance of several important substances. These include phosphorus, calcium, parathyroid hormone, and vitamin D. When you have chronic kidney disease, your body no longer keeps the right balance of these substances. This can lead to bone disease.

Detailed explanation-4: -Renal osteodystrophy is a complication of chronic kidney disease that weakens your bones. It’s caused by changes in the levels of minerals and hormones in your blood. The main signs are bone pain and fractures. There’s no cure except for a kidney transplant.

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