GENERAL HISTOLOGY

Detailed explanation-1: -As blood osmolarity decreases, a negative feedback mechanism reduces osmoreceptor activity in the hypothalamus, and ADH secretion is reduced. ADH release can be reduced by certain substances, including alcohol, which can cause increased urine production and dehydration.

Detailed explanation-2: -Answer and Explanation: The release of antidiuretic hormone or ADH by the pituitary gland-the posterior lobe, in particular-is an example of negative feedback.

Detailed explanation-3: -ADH is a small peptide secreted by the posterior pituitary gland. There are two major stimuli for ADH release: elevated plasma osmolality and decreased effective circulating volume. Increased plasma osmolality causes shrinkage of a specialized group of cells in the hypothalamus called osmoreceptors.

Detailed explanation-4: -The main role of the posterior pituitary is to store and releases two hormones: oxytocin and antidiuretic hormone (ADH, or vasopressin). Both of the lobes of your pituitary gland are connected to your hypothalamus (a part of your brain) through a stalk that contains blood vessels and nerve cells.