GENERAL HISTOLOGY

EXCRETORY SYSTEM

KIDNEY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Which of the following statements about autosomal dominant polycystic kidney disease is correct?
A
Children of an affected parent have a 25% chance of inheriting the disease
B
Multiple fluid-filled cysts form in the kidneys.
C
Progression to end-stage kidney disease is highly variable.
D
Symptoms typically appear in adults aged in their 30s to 60s.
Explanation: 

Detailed explanation-1: -Autosomal dominant polycystic kidney disease (ADPKD) is an inherited condition that causes small fluid-filled sacs called cysts to develop in the kidneys.

Detailed explanation-2: -ADPKD affects 1 in every 400 to 1, 000 people and is the most common kidney disorder passed down through family members. Health care providers usually diagnose ADPKD between the ages of 30 and 50, when signs and symptoms start to appear, which is why it is sometimes called “adult PKD.”

Detailed explanation-3: -Autosomal dominant (or adult) PKD is the most common form. Symptoms usually develop between the ages of 30 and 40, but they can begin during childhood. In this form of the disease, if one of the parents carries the disease gene, the child has a 50/50 chance of inheriting the disease.

Detailed explanation-4: -The signs and symptoms of ADPKD, such as pain, high blood pressure, and kidney failure, are also PKD complications. In many cases, ADPKD does not cause signs or symptoms until your kidney cysts are a half inch or larger in size.

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