GENERAL HISTOLOGY

EXCRETORY SYSTEM

KIDNEY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Why is the recipient’s immune system less likely to attack if the organ/s donated belong/s to a relative?
A
Because they have similar immune systems.
B
Because the antigens on their cells are similar to each other.
C
Because the cell membranes are similar to each other.
D
Because they are related by blood.
Explanation: 

Detailed explanation-1: -Your immune system learns to see these antigens as normal and usually does not react against them. Innate, or nonspecific, immunity is the defense system with which you were born. It protects you against all antigens. Innate immunity involves barriers that keep harmful materials from entering your body.

Detailed explanation-2: -This is because the person’s immune system detects that the antigens on the cells of the organ are different or not “matched.” Mismatched organs, or organs that are not matched closely enough, can trigger a blood transfusion reaction or transplant rejection.

Detailed explanation-3: -Improving compatibility testing between donor and recipient could also reduce the risk of transplant rejection and increase the longevity of the transplant. The better matched the donor and the recipient are, the more tolerant the recipient’s immune system will be to the transplanted organ or tissue.

Detailed explanation-4: -The immune response to a transplanted organ consists of both cellular (lymphocyte mediated) and humoral (antibody mediated) mechanisms. Although other cell types are also involved, the T cells are central in the rejection of grafts. The rejection reaction consists of the sensitization stage and the effector stage.

There is 1 question to complete.