GENERAL HISTOLOGY

Detailed explanation-1: -After someone is diagnosed with kidney cancer, doctors will try to figure out whether it has spread, and if so, how far. This process is called staging.

Detailed explanation-2: -The exact causes of kidney cancer, like many other cancers, are not known. However, we do know that certain things can increase your chances of developing kidney cancer. Older age, smoking, obesity, high blood pressure, long-term dialysis, and a family history of kidney cancer can all increase your risk.

Detailed explanation-3: -Based on the current evidence, cigarette smoking, obesity, and hypertension are the most well-established risk factors for sporadic RCC worldwide. Acquired cystic kidney disease is also a significant risk factor, specifically in dialysis patients.

Detailed explanation-4: -Renal cell carcinoma (RCC), the most common kidney tumor, grossly invades into large vessels. Tumor extensions (so called tumor thrombi [TT]) into the renal vein are observed in approximately 15% of RCC patients. These TT are able to traverse extensive distances arriving sometimes to the heart.