GENERAL HISTOLOGY

Detailed explanation-1: -Oogenesis is the creation of an egg (also known as an ovum or oocyte) in the female foetus. Oogenesis starts in the foetus at around 7 weeks’ gestation, when primordial germ cells colonize the newly formed ovary. They are now referred to as oogonia. Oogonia undergo mitosis or rapid proliferation (multiplication).

Detailed explanation-2: -These primordial germ cells migrate to the developing gonads, which will form the ovaries in females and the testes in males. After a period of mitotic proliferation, the primordial germ cells undergo meiosis and differentiate into mature gametes-either eggs or sperm.

Detailed explanation-3: -Mammalian primordial germ cells form and migrate to the gonad during embryonic development. After arriving at the gonad, the germ cells are called oogonia and develop in clusters of cells called germ line cysts or oocyte nests. Subsequently, the oogonia enter meiosis and become oocytes.

Detailed explanation-4: -In oogenesis, diploid oogonium go through mitosis until one develops into a primary oocyte, which will begin the first meiotic division, but then arrest; it will finish this division as it develops in the follicle, giving rise to a haploid secondary oocyte and a smaller polar body.

Detailed explanation-5: -Through incomplete division of the cytoplasm (incomplete cytokinesis) during mitosis, oogonia form germ cell cysts that will develop into ovarian follicles [21].