GENERAL HISTOLOGY

Detailed explanation-1: -The hypothalamus secretes GnRH in a pulsatile fashion, which triggers FSH and LH release from the anterior pituitary. These, in turn, act on the granulosa and theca cells in the ovary to stimulate follicle maturation and trigger ovulation.

Detailed explanation-2: -Ovulation is the release of an egg from a woman’s ovaries and is essential for getting pregnant. Ovulation is spontaneously triggered about 36-40 hours after blood levels of a hormone called luteinizing hormone (LH) rise. This is called the LH surge.

Detailed explanation-3: -Luteinizing hormone is a part of a neurological pathway comprised of the hypothalamus, the pituitary gland, and gonads. In this pathway, LH release is stimulated by gonadotropin-releasing hormone (GnRH) and inhibited by estrogen in females and testosterone in males.

Detailed explanation-4: -LH surge and ovulation The LH surge sends a signal from the brain to the ovary that an egg is ready to be released from the ovary. When the follicle sees this hormone increase, it completes maturation of the egg and allows it to be released from the ovary (aka ovulation).