GENERAL HISTOLOGY

Detailed explanation-1: -Prolactin. Prolactin is necessary for the secretion of milk by the cells of the alveoli. The level of prolactin in the blood increases markedly during pregnancy, and stimulates the growth and development of the mammary tissue, in preparation for the production of milk (19).

Detailed explanation-2: -Prolactin (PRL) released from lactotrophs of the anterior pituitary gland in response to the suckling by the offspring is the major hormonal signal responsible for stimulation of milk synthesis in the mammary glands.

Detailed explanation-3: -Prolactin levels will only spike during periods of nipple stimulation through suckling by your baby. As long as your baby maintains suckling, prolactin levels stay elevated. During periods when you’re not breastfeeding, your prolactin levels decrease, and milk production reduces.

Detailed explanation-4: -The two primary hormones that are needed for lactation are prolactin and oxytocin. Prolactin stimulates milk biosynthesis within the alveolar cells of the breast and oxytocin stimulates contraction of the myoepithelial cells that surround the alveoli, causing the milk to be ejected into the ducts leading to the nipple.