GENERAL HISTOLOGY

Detailed explanation-1: -Merkel cells are touch-sensitive cells that transduce touch via Piezo2 channels. The Merkel cell-neurite complex contains two sensory receptor cell types. Merkel cells and neurons together mediate different aspects of touch responses.

Detailed explanation-2: -A special type of cell found right below the epidermis (top layer of skin). These cells are very close to the nerve endings that receive the sensation of touch and may be involved in touch. The cells also contain substances that may act as hormones.

Detailed explanation-3: -Merkel cells function as type 1 mechano-receptors and can sense light touches. They are part of the tactile-end organs in the skin, which include Merkel discs, Pacinian corpuscles, Meissner’s corpuscles, and Ruffini endings [30].