GENERAL HISTOLOGY

INTEGUMENTERY SYSTEM

DERMIS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
What cell detects produces an immune response against pathogens entering the skin?
A
Keratinocytes
B
Melanocytes
C
Merkel (Tactile) Cells
D
Langerhans (Dendritic) cell
Explanation: 

Detailed explanation-1: -Dermal Dendritic Cells. Dendritic cells that reside in the dermis are known as dermal dendritic cells (dDCs). In a similar manner to LCs, dDCs migrate to the lymph nodes, and are professional antigen-presenting cells efficient at priming adaptive immune responses [117, 118].

Detailed explanation-2: -White blood cells are the key players in your immune system. They are made in your bone marrow and are part of the lymphatic system. White blood cells move through blood and tissue throughout your body, looking for foreign invaders (microbes) such as bacteria, viruses, parasites and fungi.

Detailed explanation-3: -Dendritic cells identify antigens via pathogen-associated molecular patterns (PAMPS) or damage-associated molecular patterns (DAMPs). Comprised of molecules common to a variety of organisms but absent in the host, PAMPS are an exogenous signal to dendritic cells for infection.

Detailed explanation-4: -Dendritic cells (DCs) are professional antigen presenting cells that inform the fight against invasive pathogens while enforcing tolerance to self and harmless environmental antigens. They capture pathogens and receive signals from pathogens that influence the outcome of immune responses.

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