GENERAL HISTOLOGY

Detailed explanation-1: -The dermis, found beneath the epidermis, contains connective tissue, hair follicles, blood vessels, lymphatic vessels, and sweat glands.

Detailed explanation-2: -The largest blood supply, the subcutaneous/deep dermal supply, is composed of arteries and veins that branch superficially into the middermis to form the cutaneous plexus. The cutaneous plexus is responsible for supplying blood to the adnexal structures of the dermis, including follicles and glands.

Detailed explanation-3: -The epidermis contains no blood vessels, and cells in the deepest layers are nourished by diffusion from blood capillaries present in the upper layers of the dermis. The papillary region of the dermis is composed of loose areolar connective tissue.

Detailed explanation-4: -The skin has three layers: the epidermis; the dermis, which is composed of a narrow superficial papillary and a thicker and more profound reticular layer, and the hypodermis. Whereas the epidermis does not contain blood vessels, the dermis and hypodermis are extensively vascularized.