GENERAL HISTOLOGY

Detailed explanation-1: -Pacinian corpuscles are rapidly adapting (phasic) receptors that detect gross pressure changes and vibrations in the skin. Any deformation in the corpuscle causes action potentials to be generated by opening pressure-sensitive sodium ion channels in the axon membrane.

Detailed explanation-2: -Pacinian corpuscles represent special nerve endings that serve as mechanoreceptors sensitive to vibration and pressure and are crucial for proprioception.

Detailed explanation-3: -[8] Mechanoreceptors respond to physical changes including touch, pressure, vibration, and stretch.

Detailed explanation-4: -The lamellar corpuscles (also known as Pacinian corpuscles) in the skin and fascia detect rapid vibrations (of about 200–300 Hz). Cutaneous mechanoreceptors respond to mechanical stimuli that result from physical interaction, including pressure and vibration.