GENERAL HISTOLOGY

Detailed explanation-1: -The stratum corneum is the outer layer of your epidermis (skin). It’s made up of mostly keratin and lipids. The visible cells shed and are replaced from the lower epidermal layers. The cells have a 2-week cycle in the stratum corneum.

Detailed explanation-2: -The stratum corneum is the outermost layer of the epidermis and marks the final stage of keratinocyte maturation and development. Keratinocytes at the basal layer of the epidermis are proliferative, and as the cells mature up the epidermis, they slowly lose proliferative potential and undergo programmed destruction.

Detailed explanation-3: -The stratum corneum functions to form a barrier to protect underlying tissue from infection, dehydration, chemicals and mechanical stress. Desquamation, the process of cell shedding from the surface of the stratum corneum, balances proliferating keratinocytes that form in the stratum basale.