GENERAL HISTOLOGY

Detailed explanation-1: -The stratum spinosum (or spinous layer/prickle cell layer) is a layer of the epidermis found between the stratum granulosum and stratum basale . This layer is composed of polyhedral keratinocytes.

Detailed explanation-2: -The stratum spinosum helps make your skin flexible and strong. Between the stratum spinosum layer and the stratum lucidum layer. Keratinocytes have granules within them, and in this layer they’re visible under a microscope. Between the stratum granulosum and the stratum corneum.

Detailed explanation-3: -Keratinocytes represent the major cell type of the epidermis, the outermost of the layers of the skin, making up about 90 percent of the cells there. They originate in the deepest layer of the epidermis, the stratum basale and move up to the final barrier layer of the skin, the stratum corneum.