GENERAL HISTOLOGY

Detailed explanation-1: -The stratum basale is a single layer of columnar or cuboidal basal cells. The cells are attached to each other and to the overlying stratum spinosum cells by desmosomes and hemidesmosomes. The nucleus is large, ovoid and occupies most of the cell.

Detailed explanation-2: -The epidermal stem cells lie in the basal layer, attached to the basal lamina. Progeny that become committed to differentiation go through several rapid divisions in the basal layer, and then stop dividing and move out toward the surface of the skin.

Detailed explanation-3: -Producing new skin cells. New skin cells develop at the bottom layer of your epidermis (stratum basale) and travel up through the other layers as they get older. They reach the outermost layer of your epidermis after about a month, where the skin cells shed from your body as new cells develop at the bottom layer.