GENERAL HISTOLOGY

Detailed explanation-1: -It shields the body against heat, light, injury, and infection. The skin also helps regulate body temperature, gathers sensory information from the environment, stores water, fat, and vitamin D, and plays a role in the immune system protecting us from disease.

Detailed explanation-2: -Nerves in the skin Both the dermis and epidermis have nerve endings. These carry information about temperature, sensation (pleasure or pain) and pressure. Some areas have more of these nerves than others, such as the fingertips.

Detailed explanation-3: -The nerve endings sense pain, touch, pressure, and temperature. Some areas of the skin contain more nerve endings than others. For example, the fingertips and toes contain many nerves and are extremely sensitive to touch. The sweat glands produce sweat in response to heat and stress.

Detailed explanation-4: -Most of the nerve fibers are found in the mid-dermis and the papillary dermis. The epidermis, blood vessels, and skin appendages such as hair follicles, sebaceous glands, sweat glands, and apocrine glands are innervated by several subtypes of sensory nerves (622, 811).