GENERAL HISTOLOGY

Detailed explanation-1: -Melanin is a substance in your body that produces hair, eye and skin pigmentation. The more melanin you produce, the darker your eyes, hair and skin will be. The amount of melanin in your body depends on a few different factors, including genetics and how much sun exposure your ancestral population had.

Detailed explanation-2: -Melanin is brown, non-refractile, and finely granular with individual granules having a diameter of less than 800 nanometers. This differentiates melanin from common blood breakdown pigments, which are larger, chunky, and refractile, and range in color from green to yellow or red-brown.

Detailed explanation-3: -Melanin is predominantly restricted to the basal layer (or Stratum basale) of the human epidermis, where it is found in both melanocytes (MCs), the cells that make melanin, and in nearby keratinocytes (KCs), the cells of the epidermis that accept melanin.

Detailed explanation-4: -Melanin is produced by specialized cells called melanocytes. Melanocytes are scattered among other cells in the deepest layer of the outer layer of the skin (epidermis) called the basal layer. After melanin is produced, it spreads into other nearby skin cells.