GENERAL HISTOLOGY

Detailed explanation-1: -Third-degree burns destroy the epidermis and dermis. Third-degree burns may also damage the underlying bones, muscles, and tendons. When bones, muscles, or tendons are also burned, this may be referred to as a fourth-degree burn. The burn site appears white or charred.

Detailed explanation-2: -First-degree burns affect only the outer layer of the skin. They cause pain, redness, and swelling. Second-degree burns affect both the outer and underlying layer of skin. They cause pain, redness, swelling, and blistering.

Detailed explanation-3: -As the outermost layer of the organism, the epidermis is constantly exposed to multiple forms of injury. Failure to re-epithelialize injured skin causes the loss of the barrier function of the organ, dehydration, infection or even death.