GENERAL HISTOLOGY

INTEGUMENTERY SYSTEM

INTEGUMENTERY SYSTEM MISCELLENOUS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
How do keratinocytes change as they move upward?
A
They get flatter
B
They become squared
C
They get fatter
D
They become round
Explanation: 

Detailed explanation-1: -Keratinocytes proliferate in the basal layer of the epidermis and start differentiating on their way to the surface, undergoing gradual differentiation. During this process, they profoundly change their morphology and start to produce keratin, cytokines, growth factors, interleukins and complement factors.

Detailed explanation-2: -The keratinocytes from the squamous layer are then pushed up through two thin epidermal layers called the stratum granulosum and the stratum lucidum. As these cells move further towards the surface of the skin, they get bigger and flatter and adhere together, and then eventually become dehydrated and die.

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