GENERAL HISTOLOGY

Detailed explanation-1: -The stratum corneum is the outermost layer of the epidermis, and is made up of 10 to 30 thin layers of continually shedding, dead keratinocytes.

Detailed explanation-2: -Keratinocytes are the predominant cell type of epidermis and originate in the basal layer, produce keratin, and are responsible for the formation of the epidermal water barrier by making and secreting lipids.

Detailed explanation-3: -Stratum Granulosum The cells (three to five layers deep) become flatter, their cell membranes thicken, and they generate large amounts of the proteins keratin, which is fibrous, and keratohyalin, which accumulates as lamellar granules within the cells (see Figure 5.1.

Detailed explanation-4: -The epidermis, the outermost layer of skin, provides a waterproof barrier and creates our skin tone. The dermis, beneath the epidermis, contains tough connective tissue, hair follicles, and sweat glands. The deeper subcutaneous tissue (hypodermis) is made of fat and connective tissue.