GENERAL HISTOLOGY

Detailed explanation-1: -Melanocytes are derived from neural crest cells and primarily produce melanin, which is responsible for the pigment of the skin. They are found between cells of stratum basale and produce melanin.

Detailed explanation-2: -Melanin is predominantly restricted to the basal layer (or Stratum basale) of the human epidermis, where it is found in both melanocytes (MCs), the cells that make melanin, and in nearby keratinocytes (KCs), the cells of the epidermis that accept melanin.

Detailed explanation-3: -Melanocytes are ideally positioned in the epidermis to be sentinels against harmful pathogens. Melanocytes reside in the stratum basale, the lowest layer of the epidermis, but they use their dendrites to interact with cells in other layers, and to capture pathogens that enter the epidermis.