GENERAL HISTOLOGY

Detailed explanation-1: -The squamous cell layer is the thickest layer of the epidermis, and is involved in the transfer of certain substances in and out of the body. The squamous cell layer also contains cells called Langerhans cells.

Detailed explanation-2: -Langerhans cells, dendritic cells, are the skins first line defenders and play a significant role in antigen presentation. These cells need special stains to visualize, primarily found in the stratum spinosum.

Detailed explanation-3: -Langerhans cells (LCs) reside in the epidermis as a dense network of immune system sentinels. These cells determine the appropriate adaptive immune response (inflammation or tolerance) by interpreting the microenvironmental context in which they encounter foreign substances.