GENERAL HISTOLOGY

Detailed explanation-1: -"Xanthoderma” is a term that describes a yellow to orange macular discoloration of the skin. The cause of this finding ranges from benign to potentially life-threatening disease. To date the literature fails to comprehensively review the various causes and workup of this clinical manifestation.

Detailed explanation-2: -Jaundice is a condition in which the skin, whites of the eyes and mucous membranes turn yellow because of a high level of bilirubin, a yellow-orange bile pigment. Jaundice has many causes, including hepatitis, gallstones and tumors. In adults, jaundice usually doesn’t need to be treated.

Detailed explanation-3: -Yellow skin is often the result of liver damage that leads to a build-up of bilirubin. 10 However, there are a number of other issues that can cause yellowing skin, including a blocked bile duct, genetic disorders, or eating too many carotene-rich foods such as carrots.

Detailed explanation-4: -First described in 1919 by Hess and Meyers, carotenemia is the medical terminology describing yellow-orange skin pigmentation due to high carotene levels in the blood. Excessive consumption of fruits and vegetables high in carotene content is often the culprit.