GENERAL HISTOLOGY

Detailed explanation-1: -The epidermis contains no blood vessels, and cells in the deepest layers are nourished by diffusion from blood capillaries present in the upper layers of the dermis.

Detailed explanation-2: -Using immunohistochemical procedures numerous nerve fibers have been found in all cell layers of human epidermis. These nerves originate from nerve trunks in the dermis, enter the epidermis, then divide distally to eventually end in small enlargements, near the surface of the skin and in deeper areas.

Detailed explanation-3: -The epidermis does not contain any blood vessels or nerve fibers, it only contains keratinized epithelial cells that are constantly replaced, they do not get many nutrients, and anything they get is through diffusion.