GENERAL HISTOLOGY

Detailed explanation-1: -The dermis houses blood vessels, nerve endings, hair follicles, and glands. There are many cell types found within the connective tissue of the dermis, including fibroblasts, macrophages, adipocytes, mast cells, Schwann cells, and stem cells. [5] Fibroblasts are the principal cell of the dermis.

Detailed explanation-2: -It also contains more than 1, 000 nerve endings that sense touch, pain, temperature and pressure. When one of those nerve endings is stimulated, a signal is sent to the brain, and you “feel” the corresponding sensation. Skin is the first line of defense against germs that could enter the body and make you sick.

Detailed explanation-3: -The dermis has a rich layer of blood and lymphatic vessels, including the arteriovenous anastomoses important in thermoregulation. The dermis also contains numerous nerve endings, including a wide variety of the cutaneous sensory nerve receptors.