GENERAL HISTOLOGY

Detailed explanation-1: -The ribosome is a complex molecule made of ribosomal RNA molecules and proteins that form a factory for protein synthesis in cells. In 1955, George E. Palade discovered ribosomes and described them as small particles in the cytoplasm that preferentially associated with the endoplasmic reticulum membrane.

Detailed explanation-2: -In eukaryotic cells, however, the two processes are separated in both space and time: mRNAs are synthesized in the nucleus, and proteins are later made in the cytoplasm.

Detailed explanation-3: -The nucleolus is composed of RNA and proteins, which form around specific chromosomal regions. It is one of the main components of the nucleus. The chain of RNA and DNA along with other components form the structural components.

Detailed explanation-4: -Ribosomal genes and RNA are transcribed in small regions of the nucleolus known as the “fibrillar center (FC)” and “dense fibrillar component (DFC)”. The bulk of the nucleolus is the granular component (GC), where rRNA and proteins assemble to the ribosomal subunit (Fig.

Detailed explanation-5: -All living cells contain ribosomes, tiny organelles composed of approximately 60 percent ribosomal RNA (rRNA) and 40 percent protein.