GENERAL HISTOLOGY

Detailed explanation-1: -Microtubules are microscopic, hollow tubes made of alpha and beta-tubulin that are a part of the cell’s cytoskeleton. They help in aligning and separating the chromosomes during the metaphase and anaphase stages of cell division. They form spindle fibres that get attached to the chromosomes during cell division.

Detailed explanation-2: -Cytoskeletal filaments provide the basis for cell movement. For instance, cilia and (eukaryotic) flagella move as a result of microtubules sliding along each other. In fact, cross sections of these tail-like cellular extensions show organized arrays of microtubules.

Detailed explanation-3: -In addition to playing this structural role, the cytoskeleton is responsible for cell movements. These include not only the movements of entire cells, but also the internal transport of organelles and other structures (such as mitotic chromosomes) through the cytoplasm.

Detailed explanation-4: -Metaphase leads to anaphase, during which each chromosome’s sister chromatids separate and move to opposite poles of the cell. Enzymatic breakdown of cohesin-which linked the sister chromatids together during prophase-causes this separation to occur.

Detailed explanation-5: -microtubules. Microtubules are the cytoskeleton structure that is made up of tubulin protein that provides structure and shape to the cells. During mitosis cell division several microtubules get activated and move to the chromosome.