GENERAL HISTOLOGY

Detailed explanation-1: -Phagocytosis is an important process for nutrition in unicellular organisms, while in multicellular organisms it is found in specialized cells called phagocytes. Phagocytosis consists in recognition and ingestion of particles larger than 0.5 m into a plasma membrane derived vesicle, known as phagosome.

Detailed explanation-2: -Phagocytes are cells that recognize pathogens and destroy them through phagocytosis. Recognition often takes place by the use of phagocyte receptors that bind molecules commonly found on pathogens, known as pathogen-associated molecular patterns (PAMPs).

Detailed explanation-3: -Phagocytosis is the process of sensing and taking in particles larger than 0.5 m. The particle is internalized into a distinctive organelle, the phagosome. This phagosome subsequently changes the structure of its membrane and the composition of its contents in a process known as phagosome maturation (3).

Detailed explanation-4: -During phagocytosis, cells are able to ingest large particles (greater than 0.5 µm in diameter) which serves not only to engulf and destroy invading bacteria and fungi but also to clear cellular debris at wound sites and to dispose of aged erythrocytes.