GENERAL HISTOLOGY

Detailed explanation-1: -Ribosomes that synthesize proteins destined for insertion into cellular membranes or for export from the cell associate with specialized regions of the ER, called the rough ER owing to the attached ribosomes. Cell type-dependent and may function in lipid synthesis, carbohydrate metabolism, and drug detoxification.

Detailed explanation-2: -The ER has a central role in lipid and protein biosynthesis. Its membrane is the site of production of all the transmembrane proteins and lipids for most of the cell’s organelles, including the ER itself, the Golgi apparatus, lysosomes, endosomes, secretory vesicles, and the plasma membrane.

Detailed explanation-3: -The rough endoplasmic reticulum (rough ER) gets its name from the bumpy ribosomes attached to its cytoplasmic surface. As these ribosomes make proteins, they feed the newly forming protein chains into the lumen.

Detailed explanation-4: -The endoplasmic reticulum (ER) is a membranous organelle that shares part of its membrane with that of the nucleus. Some portions of the ER, known as the rough ER, are studded with ribosomes and are involved with protein manufacture.

Detailed explanation-5: -The endoplasmic reticulum can either be smooth or rough, and in general its function is to produce proteins for the rest of the cell to function. The rough endoplasmic reticulum has on it ribosomes, which are small, round organelles whose function it is to make those proteins.